Module also offered within study programmes:
General information:
Name:
Neuroelectronics
Course of study:
2016/2017
Code:
JBF-3-008-s
Faculty of:
Physics and Applied Computer Science
Study level:
Third-cycle studies
Specialty:
-
Field of study:
Biophysics
Semester:
0
Profile of education:
Academic (A)
Lecture language:
Polski i Angielski
Form and type of study:
Full-time studies
Course homepage:
 
Responsible teacher:
prof. dr hab. inż. Dąbrowski Władysław (w.dabrowski@ftj.agh.edu.pl)
Academic teachers:
dr inż. Hottowy Paweł (hottowy@agh.edu.pl)
prof. dr hab. inż. Dąbrowski Władysław (w.dabrowski@ftj.agh.edu.pl)
Module summary

Description of learning outcomes for module
MLO code Student after module completion has the knowledge/ knows how to/is able to Connections with FLO Method of learning outcomes verification (form of completion)
Skills
M_U001 Student is able to survey scientific papers on development and applications of neuroelectronic interfaces and make a seminar presentation. BF3A_U02, BF3A_U01, BF3A_U04 Presentation
Knowledge
M_W001 Student has basic knowledge of biophysical aspects of neuron-electrode interactions. BF3A_W02, BF3A_W03, BF3A_W01 Examination
M_W002 Student has basic knowledge of applications of electronic implants to treatment of neurodegenerative diseases. BF3A_W02, BF3A_W01 Examination
M_W003 Student knows about current developments of neuroelectronic interfaces and their applications in neurobiological and biomedical research. BF3A_W02, BF3A_W01 Examination
FLO matrix in relation to forms of classes
MLO code Student after module completion has the knowledge/ knows how to/is able to Form of classes
Lecture
Audit. classes
Lab. classes
Project classes
Conv. seminar
Seminar classes
Pract. classes
Zaj. terenowe
Zaj. warsztatowe
Others
E-learning
Skills
M_U001 Student is able to survey scientific papers on development and applications of neuroelectronic interfaces and make a seminar presentation. - - - - - + - - - - -
Knowledge
M_W001 Student has basic knowledge of biophysical aspects of neuron-electrode interactions. + - - - - - - - - - -
M_W002 Student has basic knowledge of applications of electronic implants to treatment of neurodegenerative diseases. + - - - - - - - - - -
M_W003 Student knows about current developments of neuroelectronic interfaces and their applications in neurobiological and biomedical research. + - - - - - - - - - -
Module content
Lectures:

1. Basic methods of imaging of brain activity. Advantages and disadvantages of recording neural activity using extracellural microelectrodes. Measurement techniques based on multielectrode arrays ((dissociated culture, organotypic culture, acute slice, in-vivo).

2. Biophysical basic of recording activity of neural cells using extracellural microelectrodes. Characteristics of signal from a single neuron (single-unit activity) and from a group of neurons (single-unit activity). Methods of classification of extracellural signals. Biophysical basics and interpretation of local field potentials.

3. Electrical stimulation of neuronal cells using extracellural electrodes. Biophysical basics; threshold current, rheobase current, chronaxie. Response of the cell body and of the axon. Direct and indirect activation of neural cells, stimulation range.

4. Electrical characteristics of microelectrodes. Equivalent electrical circuit, models of double layer impedance. Electrochemical resistivity. Reversible and nonreversible reactions. Electrochemical reaction and safe stimulation. Methods of reducing microelectrode impedance.

5. Recording of signals from large populations of neuronal cells. Architectures of large scale recording systems. Front-end electronics, noise analysis of the electrode-amplifier circuit. Examples of the state-of-the-art systems. Examples of applications in neurobiological research.

6. Simultaneous electrical stimulation and recording from large populations of neuronal cells. Mechanism of generation of stimulation artefacts. Methods of artefact reduction in current multielectrode systems. Examples of application of electrical stimulation in neurobiological and biomedical research.

7. Neuroprosthetics. Visual and auditory prosthetics – basic research and applications. Fepp brain stimulation in Parkinson’s disease and depression.

Seminar classes:

Students prepare presentation on given subjects in the area of neuroelectronic interfaces used in neurobiological research and biomedical engineering based on textbooks and current scientific literature. Each presentation is based on a specific scientific paper published in recent years. Subjects of the presentations are closely related to the topics presented in the lectures. Students should demonstrate that they are able to (a) analyse an original scientific paper and find all additional information needed to understand the subject, (b) to make a presentation and discuss the presented material.

Student workload (ECTS credits balance)
Student activity form Student workload
Summary student workload 52 h
Module ECTS credits 3 ECTS
Participation in lectures 15 h
Preparation for classes 5 h
Preparation of a report, presentation, written work, etc. 15 h
Participation in seminar classes 15 h
Examination or Final test 2 h
Additional information
Method of calculating the final grade:

Grade composition
Exam – 50%
Seminar presentation – 50%

Final grade
< 50% – failed
50-60% – 3,0
61-70% – 3,5
71-80% – 4,0
81-90% – 4,5
91-100% – 5,0

Prerequisites and additional requirements:

Basics of neural cell biology, Understanding of action potential. Basics of physics, and electronics.

Recommended literature and teaching resources:

Fundamentals:
1. Matthews GG: Neurobiologia – od cząsteczek i komórek do układów. Wydawnictwo Lekarskie PZWL, Warszawa, 2000.
2. Hottowy P: Opracowanie modelu matryc mikroelektrodowych oraz układu scalonego do elektrycznej stymulacji żywych sieci neuronowych. Rozprawa doktorska, Akademia Górniczo-Hutnicza, 2006.
3. Gosselin B: Recent advances in neural recording microsystems. Sensors vol. 11, pp. 4572-4597, 2011. (open access: http://www.mdpi.com/1424-8220/11/5/4572/pdf)

Specific scientific papers for seminar topics are indicated individually for each student by the teacher.

Scientific publications of module course instructors related to the topic of the module:

Additional scientific publications not specified

Additional information:

None