Module also offered within study programmes:
General information:
Name:
Physics of nanomagnetism and some biomedical applications.
Course of study:
2016/2017
Code:
JBF-3-024-s
Faculty of:
Physics and Applied Computer Science
Study level:
Third-cycle studies
Specialty:
-
Field of study:
Biophysics
Semester:
0
Profile of education:
Academic (A)
Lecture language:
English
Form and type of study:
Full-time studies
Course homepage:
 
Responsible teacher:
prof. dr hab. Burda Kvetoslava (kvetoslava.burda@fis.agh.edu.pl)
Academic teachers:
Module summary

Physical background of magnetism and interactions between magnetic nanoparticles and biomaterials will be presented. Their potential applications in new biotechnologies and medicine will be discussed.

Description of learning outcomes for module
MLO code Student after module completion has the knowledge/ knows how to/is able to Connections with FLO Method of learning outcomes verification (form of completion)
Social competence
M_K001 Student will understand the importance of continuous learning and combining knowledge from different fields of knowledge. Student will be able to formulate new problems and search for their solution. BF3A_K01 Participation in a discussion
Skills
M_U001 Student will understand physical background of magnetism and interactions between magnetic nanoparticles and biomaterials. Student will be able to indicate their potential applications in new biotechnologies and medicine. BF3A_U02, BF3A_U01 Presentation
M_U002 Student is capable of reading and understanding papers on a given scientific problem. Student can present seminar using this knowledge. BF3A_U02 Presentation
Knowledge
M_W001 Student will acquire knowledge about the magnetic nanoparticles and their potential applications in biomedicine. BF3A_W01, BF3A_W02 Presentation
FLO matrix in relation to forms of classes
MLO code Student after module completion has the knowledge/ knows how to/is able to Form of classes
Lecture
Audit. classes
Lab. classes
Project classes
Conv. seminar
Seminar classes
Pract. classes
Zaj. terenowe
Zaj. warsztatowe
Others
E-learning
Social competence
M_K001 Student will understand the importance of continuous learning and combining knowledge from different fields of knowledge. Student will be able to formulate new problems and search for their solution. + - - - - + - - - - -
Skills
M_U001 Student will understand physical background of magnetism and interactions between magnetic nanoparticles and biomaterials. Student will be able to indicate their potential applications in new biotechnologies and medicine. + - - - - + - - - - -
M_U002 Student is capable of reading and understanding papers on a given scientific problem. Student can present seminar using this knowledge. + - - - - + - - - - -
Knowledge
M_W001 Student will acquire knowledge about the magnetic nanoparticles and their potential applications in biomedicine. + - - - - + - - - - -
Module content
Lectures:
Physics of nanomagnetism and some biomedical applications.

I. INTRODUCTION
1. History of magnetic materials.
2. Current state: nanomagnetism, nanomaterials and nanotechnology.

II. THE (SHORT) CRASH-COURSE ON NANOMAGNETISM
3. The magnetic behavior of bulk materials.
4. Magnetism at small dimensions: the collapse of magnetic domains.
5. There can be only one: the single domain particle. Superparamagnetism.
6. The magnetic fingerprints of magnetic nanoparticles.
7. The surface magnetic disorder: I see dead layers.

III. MAGNETIC NANOPARTICLES AND MAGNETIC FIELDS
8. Magnetic fields: the invisible stranger.
9. Why my Pin sticks to my refrigerator? The static H-M interaction.
10. Why my mobile charger heat up while charging? Magnetic Losses and Power absorption
11. Dancing under magnetic fields: magnetic nanoparticles under radiofrequency fields.
12. The magnetic parameters: figuring out what’s really important
13. Size matters: effect of particle size and aggregation on the power absorption efficiency.
14. Physical effects of magnetic fields on biological systems. Do you care about your mobile radiation? Myths and facts.
15. Safety and limits for the magnetic field. To be or not to be (afraid of the Wifi)

IV. DO IT YOURSELF: NANOMATERIALS
16. Chemical Synthesis of magnetic nanoparticles
17. Physical Synthesis of magnetic nanoparticles
18. Functionalization of MNPs: in situ vs. ex situ methods.
19. Characterization of magnetic nanoparticles.
20. Magnetic colloids: biocompatibility, stability, reproducibility.
21. MNPs in physiological environments.

V. THE BIO-NANO INTERACTION
22. MNPs and the eukaryotic cell: a subtle interaction
23. MNPs uptake and trafficking pathways.
24. Toxicity of nanomaterials at the cell level.
25. Magnetized cells: potential for nanodiagnosis and nanotherapy.

VI. BIOMEDICAL APPLICATIONS OF MAGNETIC NANOPARTICLES: POSSIBILITIES AND LIMITATIONS.
26. Nanotechnology into the Clinics.
27. Future diagnosis and therapy protocols: here comes the sun.

VII. CONCLUSIONS

Seminar classes:
Nanomagnetism and selected biomedical applications

Oral presentations

Student workload (ECTS credits balance)
Student activity form Student workload
Summary student workload 90 h
Module ECTS credits 4 ECTS
Participation in seminar classes 20 h
Participation in lectures 40 h
Contact hours 10 h
Preparation for classes 20 h
Additional information
Method of calculating the final grade:

Grading

Oral presentation: 35 %
Paper discussions: 35 %
Debates: 30 %

Final grade
< 50% failed
50-60% 3,0
61-70% 3,5
71-80% 4,0
81-90% 4,5

Prerequisites and additional requirements:

Basic knowledge in physics, chemistry, biophysics and biochemistry.

Recommended literature and teaching resources:

Will be given during the lectures.

Scientific publications of module course instructors related to the topic of the module:

According to the list of publications available on the Web of Science.

Additional information:

Teacher responsible for the classes

Dr. Gerardo F. Goya
Instituto Universitario de
Investigación en Nanociencia de Aragón (INA).
Universidad de Zaragoza
Mariano Esquillor s/n
50018-Zaragoza

web:http://www.unizar.es/gfgoya/